SR9009 kaniini 100 kaniini/dhalo
Magaca Alaabta:SR9009
Kala fogaanshaha: 10 mg/kiniin 100 kaniini/dhalo
Qiimaha: $80 / dhalo
MOQ: 1 dhalo
Shaybaadhka:LianFu Bio
Qeexida badeecada
SR9009, REV-ERBagonist, waxay kordhisaa cadaadiska ka kooban hidde-sideyaasha ay maamusho REV-ERBα/ERBβ (IC50: 670/800 nM).Iyadoo loo marayo firfircoonida REV-ERB, SR9009 waxay yareyn kartaa dhaqdhaqaaqa wareegga wareegga inta lagu jiro marxaladda mugdiga ah waxayna bedeli kartaa qaabka muujinta hiddo-wadaha saacadaha asaasiga ah ee hypothalami ee jiirarka.Qaabka wareegga wareegga ee muujinta hiddaha dheef-shiid kiimikaadka ee beerka, murqaha lafaha, iyo unugyada adipose ayaa sidoo kale lagu beddelay jiirarka soo gaadhay SR9009, taasoo keentay kororka kharashka tamarta.
SR9009 (100 mg/kg, ip, bid, muddo 30 maalmood ah)hoos u dhigi tirada baruurtaoo si cadhagaajinta dyslipidemiaiyohyperglycemia.